Expanding codon size-Reference-Cited by-同舟云学术

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Expanding codon size

Published:2022-05-11 Issue: Volume:11 Page:
ISSN:2050-084X
Container-title:eLife
language:en
Short-container-title:

Author:

Siddika Tarana¹,Heinemann Ilka U¹^ORCID,O’Donoghue Patrick²^ORCID

Affiliation:

1. Department of Biochemistry, The University of Western Ontario

2. Department of Biochemistry, Department of Chemistry, The University of Western Ontario

Abstract

Engineering transfer RNAs to read codons consisting of four bases requires changes in tRNA that go beyond the anticodon sequence.

Publisher

eLife Sciences Publications, Ltd

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://cdn.elifesciences.org/articles/78869/elife-78869-v1.pdf

Reference10 articles.

1. Multiplex suppression of four quadruplet codons via tRNA directed evolution;DeBenedictis;Nature Communications,2021

2. Measuring the tolerance of the genetic code to altered codon size;DeBenedictis;eLife,2022

3. A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design;Dunkelmann;Nature Chemistry,2021

4. Incorporation of nonnatural amino acids into streptavidin through in vitro frame-shift suppression;Hohsaka;Journal of the American Chemical Society,1996

5. Engineering translation components for genetic code expansion;Kim;Journal of Molecular Biology,2022

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