BeatProfiler: Multimodal In Vitro Analysis of Cardiac Function Enables Machine Learning Classification of Diseases and Drugs
Author:
Affiliation:
1. Department of Biomedical Engineering, Columbia University, New York, NY, USA
2. Department of Medicine, Division of Cardiology, Columbia University Medical Center, New York, NY, USA
Funder
National Institutes of Health
National Science Foundation
National Aeronautics and Space Administration
Abramova Foundation
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Link
https://ieeexplore.ieee.org/ielam/8782705/10443311/10490213-aam.pdf
Reference52 articles.
1. Calcium and Excitation-Contraction Coupling in the Heart
2. Cardiac excitation–contraction coupling
3. Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes
4. MUSCLEMOTION
5. Image-based evaluation of contraction–relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology
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