Affiliation:
1. DNO (Deputy Nursing Officer), Sri Ramakrishna Hospital, Coimbatore.
Abstract
Brugada syndrome (BrS) is an inherited ion channel channelopathy predisposing to ventricular arrhythmias and sudden cardiac death. Originally believed to be predominantly associated with mutations in SCN5A encoding for the cardiac sodium channel, mutations of 18 genes other than SCN5A have been implicated in the pathogenesis of BrS to date. Diagnosis is based on the presence of a spontaneous or drug-induced coved-type ST segment elevation. If untreated, the irregular heartbeats even can sudden death.
Subject
General Earth and Planetary Sciences,General Environmental Science,General Medicine,General Medicine,General Medicine,Marketing,Organizational Behavior and Human Resource Management,Strategy and Management,Drug Discovery,Pharmaceutical Science,Pharmacology,General Medicine,General Medicine,General Medicine,General Medicine,Energy Engineering and Power Technology,Fuel Technology