Affiliation:
1. Minerva College of Pharmacy, Indora (H.P)
Abstract
People with diabetes need anti-diabetic medications, such as insulin, glucagon-like peptide-1 (GLP-1) and its analogues, to control their blood sugar levels. However, traditional therapies based on hypodermic injections are frequently linked to poor blood glucose management, a lack of patient compliance, and a significant risk of hypoglycaemia. Self-regulated administration, commonly referred to as closed-loop medication delivery techniques, can effectively control the release of drugs Diabetes kinetics in response to the variability in blood glucose levels exhibits great promise. therapy. The advancements in the creation and application of microneedle (MN)-array patches for transdermal. An alternative to the usual hypodermic administration approach is medication delivery. Consequently, the glucose-responsive MN-array. Recently, patches for the treatment of diabetes have garnered more interest. The most recent developments in glucose-responsive MN-array patch systems are outlined in this review. Also covered are their possibilities and obstacles for clinical translation. The ability to administer complicated medications through the skin with ease and comfort is a clinical advantage of microneedles, but they haven't made it into clinical use.