A Comprehensive Review on Buccal Drug Delivery System-Reference-Cited by-同舟云学术

A Comprehensive Review on Buccal Drug Delivery System

Published:2023-05-30 Issue: Volume: Page:139-145
ISSN:2231-5713
Container-title:Asian Journal of Pharmacy and Technology
language:en
Short-container-title:AJPT

Author:

S. Bhosale Namita¹,S. Gudur Aniket¹,Ramesan Rishi¹,D. Rane Dipasha¹,D. Arolkar Pranil¹,S. Darwajkar Afrin¹,P. Mestry Pratiksha¹,A. Jagtap Vijay¹

Affiliation:

1. Yashwantrao Bhonsale College of Pharmacy, Charathe – Vazarwadi, Tal - Sawantwadi, Dist – Sindhudurg --416510 Maharashtra.

Abstract

This analysis focuses primarily on the several benefits of the buccal drug delivery system (BDDS) over the traditional and systemic formulation. Bypassing first pass metabolism, it aids in improving bioavailability. The formulation of this medication delivery system maintains contact with the mucosal surface, improving absorption and lengthening the resident time. Although not all medications can be administered with this approach, the majority of medications can. Because the degree of mucoadhesion is a crucial phenomenon for the buccal medication delivery system, bio adhesive polymers play a significant role in this drug delivery method. The paper discusses the advantages and disadvantages of the buccal drug delivery system, the anatomy of the oral mucosa, the mechanism of drug penetration, the use of natural polymers and permeation enhancers in the buccal drug delivery system. This evaluation also addresses currently on the market products used as buccal medication delivery systems and their potential future applications.

Publisher

A and V Publications

Subject

General Medicine

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