A Review on Floating and Mucoadhesive Drug Delivery System

Abstract

The main goal of just about every drug delivery system is to supply preferred concentrations of drugs in blood and other body fluids, which would be clinically useful and non-hazardous for a long period of time. The Floating and Mucoadhesive both are coming under the novel drug delivery system in which they considered as predominantly more effective as compared to alternative drug delivery system because this formulation having direct contact with a biological system. The latest developments of FDDS and mucoadhesive including the biological and methodology factors that affect Gastrointestinal residence time, the main mucosal system which is explained, the structure of the main formulation described, approaches to develop single-unit and various different-unit floating and mucoadhesive systems, advantages, and one's categorization and development, in which the material used for floating mucoadhesive formulation preparation and other material which are shown on the rationale of their use in this formulation, aspects characterization are enlisted like Thickness and Diameter Testing, Bioadhesion Test, Drug Content Uniformity Test, X Rays Studies Water Uptake Studies, etc. This review also describes the studies to assess the effectiveness and implementation of floating systems, and applications of mucoadhesive systems.