Synthesis, Characterization, UTI and Antibacterial Activity of Schiff Base, (E)-2-(decan-2-ylidene) hydrazine-1-carboxamide Co2+, Mn2+ and Fe3+Metal Complexes

Abstract

Novel coordination complexes of Co, Mn and Fe with Azomethine (E)-2-(decan-2-ylidene) hydrazine-1-carboxamide have been synthesized and studied using elemental analysis (C, H, N), FT-IR, 1HNMR, 13 CNMR, XRD and Mass spectroscopy as well as thermal studies. The Schiff base has octahedral geometry and functions as a tridentate ONS donor ligand. The antimicrobial action of the Azomethine ligand and complexes was investigated towards Staphylococcus aureus, Escherichia coli and fungi C. albicans and A. fumigatus. Microbial pathogens invading the urinary tract produced urinary tract infections, they can cause a variety of clinical symptoms as well as potentially fatal sequelae. The current research focus on the growth of a novel antimicrobial agent towards E. coli, P. aeruginosa, K. pneumoniae bacteria.