Analgesic activity of Hydroalcholic extract of Achyranthes aspera leaves on animal model-Reference-Cited by-同舟云学术

Analgesic activity of Hydroalcholic extract of Achyranthes aspera leaves on animal model

Published:2021-11-27 Issue: Volume: Page:239-241
ISSN:2231-5691
Container-title:Asian Journal of Pharmaceutical Research
language:en
Short-container-title:AJPR

Author:

Shukla Karunakar¹,Jain Sourabh¹,Patil Narendra¹,Patil Ketan²,Wagh Kalpesh²

Affiliation:

1. Department of Pharmacology, Dr. A. P. J. Abdul Kalam University Indore, MP., India.

2. Department of Phamaceuices, KVPS Institute of Pharmaceutical Education, Boradi, MS., India.

Abstract

Achyranthes aspera L. (Family: Amaranthaceae) is widely used as a medicinal plant. The hydroalcholic extract of Achyranthes aspera L. leaves was screened for its analgesic activity. The dose (200 mg/kg) was tested for analgesic activity using hot plate and Tail flick test in albino mice. The hydroalcholic extract of Achyranthes aspera L. leaves showed maximum analgesic activity in hot plate at reaction time 120 min (7.40±0.08) and tail flick method at reaction time 120 min (6.9±0.06). These study suggest that the hydroalcholic extract of Achyranthes aspera L. could be considered as potential analgesic agent.

Publisher

A and V Publications

Reference8 articles.

1. Mehta F.A et.al.Antiociceptive and anti-inflammatory activity of Achyranthes aspera extracts. Pharmacologyonline. 2009; 3: 978-985. 2. Guyton, A.C., and Hall, J.E. Textbook of Medical Physiology. Philadelphia : Elsevier Saunders; 2006.

2. Singh, A., Malhotra, S., and Subban, R. Anti-inflammatory and analgesic agents from Indian medicinal plants. International Journal of Integrative Biology. 2008; 1: 57–72.

3. USDA-NRCS. The Plants Database. Baton Rouge. USA: National Plant Data Center.; 2012.

4. Aziz A, Rahman,et.al.. 3-Acetoxy-6-benzoyloxyapagamide from Achyranthes aspera. Journal of Pharmaceutical Sciences. 2005; 4(2): 113-116.

5. Umamaheswari M,et.al. Anticataract and antioxidant activities of Achyranthes aspera Linn. Against glucose-induced cataractogenesis using goat lenses. Journal of Natural Product and Plant Resources. 2012; 2: 153-161.