Nimesulide – A Drug to be Banned completely

Abstract

The Aim of present work is to report Nimesulide a Nonsteroildal Anti Inflammatory Drug is being sold as over the counter drug has to banned completely due to occurrence of Nimesulide induced acute hepatitis. On February 12, 2011, the Union Ministry of Health and Family Welfare finally had decided to suspend the pediatric use of the Nimesulide suspension. From 10 March 2011 Nimesulide formulations are not indicated for human use in children below 12 years of age. On September 13, 2011 Madras High Court revoked a suspension on manufacture and sale of pediatric drugs Nimesulide and phenylpropanolamine (PPA). Though the government of India has banned the pediatric use of Nimesulide for common fever and pain due to its adverse effects on the liver, its usage by adults is being increased everyday without any prescription. The drug was banned in 2000 in various countries like Switzerland, Spain, United states etc, whereas in India it was banned in 2011 which was too late to be banned and still available in India for adult use despite of its hepatotoxicity and possible drug interactions.