A Review on Diverging approaches to Fabricate Polymeric Nanoparticles

Abstract

Polymeric nanoparticles (NPs) are tiny particles with a diameter ranging from of 1 to 1000 nm that can be loaded with active compounds or surface-adsorbed onto the polymeric core. It is novel technology by which we improved therapeutic efficacy, bioavailability of API and better patient compliance. Polymeric NPs have shown promising in the delivery of drug to specific sites for the treatment of a range of disease. Polymeric nanoparticles with a size in the nanometer range protect active substance against degradation in vitro and in vivo, release the drug in a controlled manner, and allow for targeted therapy. The current review discusses polymeric nanoparticle manufacturing methods. Using polymeric drug nanoparticles to improve the therapeutic effectiveness of poorly soluble medicines in any mode of delivery is a universal approach.