Herbal Drugs used in the Management of Diabetic Nephropathy

Abstract

Diabetic nephropathy (DN) or diabetic kidney disease refers to the deterioration of kidney function seen in chronic type 1 and type 2 diabetes mellitus patients. The progression of the disease is known to occur in a series of stages and is linked to glycemic and blood pressure control. Diabetis nephropathy is a kidney disease. In normal conditions the function of kidney help to regulate fluids and salts balance in the body, which is vital for control blood pressure (BP) and protect cardiovascular condition. In Diabetic condition increases blood sugar levels in high, this sugar level increase long time of the period then these high glucose levels can damage various regions of the body including the cardiac system and kidney. Damaging of kidney that results or this condition is termed as diabetes nephropathy. The average incidence of diabetic nephropathy is high (3% per year) during the first 10 to 20 years after diabetes onset. Typically, it takes 15 years for small blood vessels in organs like kidney, eyes and nerves to get affected. It is estimated that more than 20 and up to 40% of diabetic patients will develop chronic kidney disease (CKD).