A Review on Analytical Method Development and Validation for the Simultaneous Estimation of Rosuvastatin and Fimasartan in Bulk and its Pharmaceuticle Dosage Form

Author:

Kumar Suresh1,Chavda Nirma2

Affiliation:

1. B. Pharmacy College Rampura, Kakanpur, Gujarat.

2. Research Scholar, Gujarat Technological University, Ahmedabad.

Abstract

Hypertension is a popular disease that is specified by having a lot of quantity of pressure in blood vessels than normal. High blood pressure is a very general disorder, especially past middle age. It is a vital risk issue for cardiovascular mortality. For enhanced activity of hypertension, Rosuvastatin and Fimasartan are newer combination in the market, which is effective in High blood pressure. This combination was developed to enhance medication for Stage II Hypertension. This article gives information about totally different analytical method development like spectrophotometric and chromatographic methods reported for Rosuvastatin and Fimasartan for individual and other drug combinations. All reported methods were found to be simple, accurate, economic, precise and reproducible in nature. This Review delivers on latest development in analytical method development for Rosuvastatin and Fimasartan, and there are no methods reported for this combination as per our knowledge.

Publisher

A and V Publications

Subject

General Medicine

Reference58 articles.

1. https://www.drugbank. ca/drugs/DB01098. Accessed 10 July2019. (Drug Bank (2019) Rosuvastatin Calcium).

2. https:// www.drugbank.ca/drugs/DB09279. Accessed 9 July 2019 (Drug Bank (2019) Fimasartan potassium trihydrate).

3. Kansara, D.A, Chhalotiya, U.K, Kachhiya, H.M. Simultaneous estimation of amlodipine besylate, Rosuvastatin calcium and Fimasartan potassium trihydrate combination used in the treatment of hypertension using LC method. SN Appl. Sci. 2.

4. Charu P. Pandya1 and Sadhana J. Rajput. Separation and characterization of major oxidative impurity in fimasartan drug substance. Rasayan J. Chem. 2018; 11(3): 1042-1049 http://dx.doi.org/10.31788/RJC.2018.1132083.

5. M. Girija, N. Kokilavani. Effectiveness of Structured Teaching Programme on Knowledge, Attitude and Practice among Patients with Hypertension. Asian J. Nur. Edu. and Research. 2014; 4(1): 136-139.

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