Pathfinder Nanosponges for Drug Targeting by Factorial Design: A Glance Review

Author:

Abdul Ahad Hindustan1,Chintaginjala Haranath1,Rahamathulla Syed1,Rupasree Aswarthanarayana1,Sajan Kumar Anegondithimmappa1,Prasanna Pallavi Barji1

Affiliation:

1. Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)- Autonomous, KR Palli Cross, Cheyyedu-515721, Ananthapuramu, Andhra Pradesh, India.

Abstract

For a long time, drug delivery systems (DDS) have been targeted to get expected results. With nanotechnology-based DDS, a wide assortment of flawless challenges can be tackled at present. Known as a nanosponge, a nanosponge is a modern division of material consisting of tiny particles that transmit only a few nanometers. The nano-formulations are highly effective for the delivery of low-solubility drugs. Many drugs with narrow therapeutic windows can benefit from improving water solubility. It has even been claimed they can be utilized to target and control delivery. In addition, huge amounts of money have been spent on developing new formulations of the DDS in recent times. Learn how nanosponges are prepared, its advantages, and its disadvantages. Resources were consulted to comprehend recent enhancements and patents in the domain. The ideal DDS has been developed by combining many different formulations; nano sponges are one of them. Analysts have examined them and found that they produce positive results and can improve the stability of poorly water-soluble drugs. The drug will be released at the precise target site when it reaches the body and sticks to the surface of the target site. As medication maximum action declines, it is more difficult to formulate impotent drugs. Considering this, nanosponges are organized and examined to determine whether they are problematic. Nanosponges in drug delivery can be characterized by their characteristics, preparation, factors, and applications. The article was written based on research articles about nanosponges. Data on nanosponges drug delivery systems from the past decade was collected using a factorial design. Study authors report that factor design plays an imperative role in optimizing drug dosage forms. Researchers will save time by reviewing the literature on nanosponges via factorial designs instead of searching for it.

Publisher

A and V Publications

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