Affiliation:
1. YSPM’s YTC Faculty of Pharmacy, Wadhe, Satara – 415011.
Abstract
Due to the presence of terpinen-4-ol as the main constituent, Melaleuca alternifolia leaves are used to produce the essential oil tea tree oil through steam distillation and supercritical fluid extraction, has discovered a wide variety of antimicrobial activities as antiviral, antifungal, and antibacterial. Tea tree oil (TTO) is among the useful products with medicinal effects due to its many benefits. Additionally, it has antimicrobial and other therapeutic properties. After around 80 years of use, anecdotal evidence suggests that applying the oil topically is generally safe and that any adverse reactions are rare, small, and self-limiting. According to published evidence, TTO can irritate the skin at high concentrations and is dangerous at greater dosages. TTO can cause allergic reactions in those who are predisposed to them, which may be brought on by the numerous the byproducts of oxidation created when the oil is exposed to air and/or light. TTO could be developmental toxic. The application of tea tree oil, its extraction method, its ingredients, safety issues, etc. are the topics covered in the current review article.