A Review on Medicinal Herbs with Potential Anti-Depressant Activities

Abstract

Depression is a state of gloomy mood and avoidance of activities marked by loss of interest, low energy, and difficulty concentrating. Inhibition of NA and 5-HT, as well as MAO-A activation, are contributing factors to the illness. Symptoms include the loss of interest in enjoyment, worthlessness or unwarranted guilt, a drop in libido and appetite, insomnia, and persistent thoughts of death or suicide. There are several synthetic medications available for the treatment of depression, but not enough and effective for patients and these drugs may also have negative effects. variety of medicinal plants and the medication generated from these plants have demonstrated antidepressant qualities. Reduced levels of monoamines including noradrenaline, dopamine, and serotonin in the brain are the causes of depression. Therefore, medications that increase the levels of these monoamines in the brain either by blocking monoamine oxidase or by increasing their reuptake may be effective in treating depression. The current analysis is concentrated on medicinal plants and formulations made from plants that have demonstrated antidepressant efficacy in both human and animal studies.