Affiliation:
1. Department of Pharmacology, Vidyabharti Collage of Pharmacy, Amravati, Maharashtra, 444602, India.
Abstract
Southeast Asian nations frequently employ Centella asiatica, also known as Centella asiatica (L.) Urb. or gotu kola, which is a traditional Chinese herb with a wide range of medical benefits. It has been noted that the medicinal plant Centella asiatica (L.) Urban, sometimes known as gotu kola, exhibits a variety of pharmacological properties. There is a substantial body of scientific study, in particular, on the therapeutic benefits of C. asiatica preparations or its triterpenes in the treatment of skin conditions. The aerial parts and roots are used medicinally, and the chemical components of this plant have a wide range of therapeutic uses, including antibacterial, anti-inflammatory, anticancer, neuroprotective, and treatments for Parkinson's disease, Alzheimer's disease, and dopamine neurotoxicity. Sedative. Immunostimulant. hepatoprotective, cardioprotective, anti-diabetic, cytotoxic and anti-tumor, antiviral, and reducing oxidative stress. a wide variety of chemicals from many chemical classes are used in antioxidant, wound healing, and other biological functions. Triterpene saponosides are this plant's main chemical class. The principal ones include betulinic acid, thankunic acid, and isothankunic acid, as well as asiatic acid, madecassic acid (6-hydroxy-asiatic acid), asiaticoside, and madasiatic acid. Additionally, we conducted a comprehensive analysis of the available literature for this review in order to determine the significance of C. asiatica in terms of pharmacology. To determine the precise method of action of other bioactive chemicals, more research will be useful.