A Cutting-Edge Method for Regulated Drug Delivery - Microencapsulation

Author:

V. Harshitha1,D. Vivek1,S. Jaipal1

Affiliation:

1. Surabhi Dayakar Rao College of Pharmacy, Siddipet, Telangana, India.

Abstract

Microencapsulation is the process of encasing, coating, or surrounding a very small droplet of particle, such as a solid, liquid, or even a gas, with a polymeric particle. In comparison to other parenteral controlled release dosage forms, such as macro-sized implants, microparticles offer a number of important benefits as drug delivery systems, including I an efficient protection of the encapsulated active agent against (e.g. enzymatic) degradation, (ii) the ability to precisely control the release rate of the incorporated drug over periods of hours to months, (iii) an easy administration, and (iv) desired, pre-programmed drug release. There are various methods to chemically encapsulate the substance, including the coacervation approach, the polymeric-polymeric incompatibility method, and the physical method, which include the centrifugal extrusion process, pan coating, spray drying, and the air suspension method. Core material, which is the required substance to be coated, and coating material are the most crucial materials utilised in microencapsulation (which is capable of forming film). Because it applies to the pharmaceutical, agricultural, food, and construction industries. Due to its precise action and minimal adverse effects, it is a better drug delivery technique than conventional drug delivery systems.

Publisher

A and V Publications

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference11 articles.

1. Vinod R, Ashok Kumar P, Amit S Yadav, Someshwara Rao B, Suresh V Kulkarni. Formulation and Evaluation of Controlled Release Microspheres of Zidovudine. Research J. Pharma. Dosage Forms and Tech. 2010; 2(1):96-99.

2. Sarika V. Khandbahale. Microencapsulation – A Novel Approach in Drug Delivery: A Review. Asian J. Res. Pharm. Sci. 2020; 10(1):39-50.

3. Ayanam Vasavi, Miriyala Mrunalini, Ayanam Vasanthi, G. Raveendra Babu, M. Sowjanya. Formulation and Evaluation of Sustained Release Stavudine Microspheres by Ionotropic Gelation Method. Asian Journal of Pharmacy and Technology. 2022; 12(2):119-4.

4. Vinod R, Ashok Kumar P, Amit S Yadav, Someshwara Rao B , Suresh V Kulkarni. Formulation and Evaluation of Controlled Release Microspheres of Zidovudine. Research J. Pharma. Dosage Forms and Tech. 2010; 2(1):96-99.

5. Rajesh Mujoriya. A review on study of microsphere. Research J. Pharma. Dosage Forms and Tech. 2012; 4(2): 80-85

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