Affiliation:
1. Department of Pharmaceutics, Aditya College of Pharmacy, ADB Road, Surampalem, Kakinada 533437, Andhra Pradesh, India.
Abstract
Nanorobotics, a rapidly evolving field at the intersection of nanotechnology and robotics, holds immense promise in revolutionizing pharmaceutical drug delivery and development. This comprehensive review article explores the various facets of nanorobotics and its pivotal role in the advancement of medicine. The article begins with an introduction to nanorobotics, providing a definition and historical background to contextualize its significance. Subsequently, it delves into nanorobotics' role in drug delivery, highlighting the challenges faced in conventional methods and the advantages of employing nanorobot-based systems. The review further explores nanorobotics in drug development, emphasizing its contribution to accelerating drug discovery and enabling personalized medicine. It discusses the different types of nanorobots utilized in pharmaceutical applications, including molecular, cellular, and hybrid systems. Additionally, the article covers the fabrication and propulsion techniques of nanorobots, along with navigation and control strategies. Furthermore, it delves into the interaction of nanorobots with biological systems and their potential applications in site-specific drug delivery and disease treatment. Ethical and regulatory considerations pertinent to nanorobotics in pharmaceuticals are also addressed. Finally, the review offers insights into future perspectives and challenges in the field, envisioning advanced drug delivery systems, targeted therapies, nanorobot swarms, and biohybrids. By comprehensively examining the subject, this review article presents a holistic understanding of nanorobotics potential in reshaping pharmaceutical practices for precision medicine and improved patient outcomes.