Affiliation:
1. Departments of Pharmaceutics, Anand Pharmacy College, Anand, Gujarat, India.
Abstract
In current scenario medical experts have long struggled with how to deliver medication to targeted location into the body while also controlling the drug release rate to avoid overdosing. This issue may be resolve through the creation of novel, intricate formulation known as nano sponges. Nano sponges are small sponge, all around size virus, that may hold a range of medication. These microscopic sponges can move through the system until they reach the intended target region, where they adhere to surface and start to release the drug in steady and controlled manner. Nano sponges are a network or 3D polyester scaffold that are spontaneously decompose. These polyesters are combined with cross-linkers agent in a solution to create a nano sponge. When loaded nano sponge’s framework breakdown the drug particle is released. They are mostly in solid form and it can be formulated as oral, parenteral, topical, or inhalation dosage form, several studies havebeen conducted on protein, peptide, genes, anti-cancer biomolecules via nano-particle technology which hep to reduce undesirable effect and enhance efficacy.
Reference34 articles.
1. Bhowmik H, venkatesh DN, Kuila A, Kumar KH. Nanosponges: a review. 2018; 10(4): 3–7.
2. Kimbonguila A, Matos L, Petit J, Scher J, Nzikou JM. Effect of physical treatment on the physicochemical, rheological and functional properties of yam meal of the cultivar “ngumvu” from dioscorea alata l. of congo. Int J Recent Sci Res. 2019; 10(c): 30693–5.
3. Bilal J. S, Abhishek S. P, Ankush S. B, Indrayani D. R, Manojkumar M. N. Nanosponges: an evolutionary trend for targeted drug delivery. Int J Pharm Sci Med. 2021; 6(6): 1–14.
4. Alongi J, Poskovic M, Frache A, Trotta F. Role of cyclodextrin nanosponges in polypropylene photooxidation. Carbohydr polym [internet]. 2011; 86(1):127–35.: http://dx.doi.org/10.1016/j.carbpol.2011.04.022
5. Pawar AY, Naik AK, Jadhav KR. Nanosponges: a novel drug delivery system. Asian J Pharm. 2016;10(4):s456–63.