Formulation, Evaluation and Phytochemical Analysis of Herbal Ointment

Abstract

Due to the existence of multiple complex chemical compounds with varying compositions that are found as secondary plant metabolites in one or more portions of medicinal plants, these plants have therapeutic powers sponding The phytoconstituents in leaf extract are what give it its antibacterial and antimicrobial properties. The goal of the study is to assess an antibacterial herbal ointment made from orange peel, pomegranate, neem, and mango leaf extracts. Evaluations of the created ointment's uniformity of weight, pH measurement, viscosity, spreadability, acute skin irritation study, stability study, and antibacterial activity were all performed on it. Our research demonstrates that MI, when made into creams and ointments for topical application, has a great potential as an antibacterial agent. Consequently, the current study draws the conclusion that the developed formulations of the MI are effective and safe carriers that have strong antibacterial properties. The mixed extract was prepared using various ointment bases, including hard paraffin, wool fat, cetostearyl alcohol, and yellow soft paraffin. The formulation's stability at different temperature conditions was also assessed, and the irritancy, spreadability, and diffusion research revealed no changes.