Affiliation:
1. Pravara Rural College of Pharmacy, Pravaranagar A/P Loni – 413736, Tal – Rahata, Dist. – Ahmednagar.
Abstract
Targeted drug delivery, particularly in the field of cosmeceutics, aims to localize pharmacologically active components at specific targets in the skin while minimizing access to non-targeted areas. Liposomes, spherical vesicles composed of phospholipids and cholesterol, have emerged as promising carriers for drug delivery due to their ability to encapsulate both hydrophilic and lipophilic drugs. They can merge with cell membranes, facilitating direct delivery of contents to targeted cells. Liposomal drug formulations have shown significant advantages in topical applications, particularly in dermatology and cosmetics. This article discusses the advantages of using liposomes in drug delivery, including the avoidance of systemic absorption and serious side effects, enhanced drug accumulation at the skin, and ease of scaling up production. Liposomes have been studied in various cosmeceutical applications, including acne treatment, hyperpigmentation and melasma, vitiligo, alopecia, and as antioxidants and UV protectants. Studies have shown the efficacy of liposomal formulations in improving therapeutic activity compared to non-liposomal counterparts, making them promising candidates for enhancing the effectiveness of cosmeceutical treatments.
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