A Review: The Potential Role of Garlic (Allium sativum L.) against Tuberculosis: Multi Drug-Resistance

Abstract

Background: Mycobacterium tuberculosis, which is responsible for tuberculosis, has become resistant to a majority of the existing antimicrobial treatments. As a result, effectively treating all tuberculosis patients has become challenging, and it's anticipated that cases of drug-resistant M. tuberculosis causing tuberculosis will rise globally. This emphasizes the pressing need for prompt detection and the creation of novel antimicrobial options to fight M. tuberculosis. When some germs become resistant to many medicines, it's hard to cure the infections they cause. It's important to look into different options for fighting TB. That's why studying natural plants, like garlic (Allium sativum), to learn about their safety and ability to fight microbes, including its various biological properties such as anti-tumour, anti-hyperlipidemic, and antimicrobial effects, is necessary. Allium sativum holds promise for creating new treatment options. Involving traditional healers in TB healthcare could aid in delivering garlic extracts to patients. Tuberculosis is a significant global cause of death, particularly when combined with AIDS. This contagious pulmonary disease spreads readily, especially in overcrowded and impoverished conditions. Garlic is a strong way to fight against infections from lots of different germs like bacteria, fungi and viruses. Using garlic to combat MDR-TB could have significant implications for public health.