Evaluation of Anthelmintic Potential in Ethanolic and Methanolic Extracts of Saraca asoca Roxb. Bark-Reference-Cited by-同舟云学术

Evaluation of Anthelmintic Potential in Ethanolic and Methanolic Extracts of Saraca asoca Roxb. Bark

Published:2024-09-02 Issue: Volume: Page:171-175
ISSN:2349-2988
Container-title:Research Journal of Science and Technology
language:en
Short-container-title:RJST

Author:

N. Girge Shubham¹,C. Kardile Vaishnavi²,M. Kawade Sakshi³,A. Thorat Kaushal⁴

Affiliation:

1. Department of Pharmaceutical Quality Assurance, Pravara Rural College of Pharmacy, Pravaranagar, SPPU University, Pune, 413713, Maharashtra, India.

2. Department of Pharmaceutical Chemistry, Dr. Vithalrao Vikhe Patil College of Pharmacy, A. Nagar, SPPU University, Pune, 414001, Maharashtra, India.

3. Department of Pharmaceutics, Parikrama College of Pharmacy, Kashti, SPPU University Pune, 414701, Maharashtra, India.

4. Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, SPPU University Pune, 413713, Maharashtra, India.

Abstract

The aim of the present study was to evaluate the anthelmintic activity of ethanolic and methanolic extracts of bark of Saraca asoca Roxb. using Pheretima posthuma as test worms. In order to compare the activity with piperazine citrate as a reference standard, the paralysis and death times were examined. The ethanolic and methanolic extracts of bark of Saraca asoca Roxb. showed a considerable anthelmintic effect as measured by a reduction in the time it took to paralyse and die. The results thus support the use of Saraca asoca Roxb. as an anthelmintic agent. Alkaloids, glycosides, tannins, flavonoids, saponins, terpenoids, and flavonoids appear to be the phytoconstituents with anthelmintic activity.

Publisher

A and V Publications

Reference11 articles.

1. Pradhan, P. Saraca asoca (Ashoka): A Review. Journal of Chemical and Pharmaceutical Research. 2009; 1(1): 62-71.

2. Borokar A. A., Dr. Pansare T. Plant Profile, Phytochemistry and Pharmacology of Ashoka (Saraca . A). International Journal of Ayurvedic and Herbal Medicine. 2017; 7(2): 2524–2541.

3. Bangajavalli, Dr. S. Tirunelveli. GC-MS analysis of bioactive componenets of bark of Saraca asoca. European Journal of Pharmaceutical. 2019.

4. Manke, Mahesh Bandappa. Helminthiasis and Medicinal plants: a Review. Asian Pacific Journal of Tropical Disease. 2015; 5.

5. Rajan, M. Suja and Suyambu. Pharmacognostical and phytochemical studies of An Ayurvedic drug Saraca asoca stem bark. Journal of Pharmacy Research. 2012;5(2): 1119-1121.