GC-MS Analysis of Phytocomponents of Methanolic Bark Extract of Sterculia foetida

Abstract

Species of the genus Sterculia have been shown to have a variety of secondary metabolites. However, there has not been the subject of significant research. This study is conducted to determine the phytocomponents in the methanolic bark extract of Sterculia foetida by GC-MS using a Shimadzu QP 2010 Ultra comprising an equipped with MS, ECD, and FID detector. This analysis revealed that the methanol extract of Sterculia foetida (bark) contained a total of 34 phytoconstituents and out of that Lupeol (63.81%), Lup-20(29)-en-3-one (5.54%) n-Hexadecenoic acid (5.73), and Vanillic acid (1.22%) were found to be in higher concentration. Lupeol has been reported to possess antiprotozoal, antimicrobial, anti-inflammatory, antioxidant, antidiabetic, antitumor, chemopreventive, and wound healing activity, while no activity was reported in Lup-20(29)-en-3-one. Vanillic acid exhibits anti-inflammatory, neuroprotective, Anti-Alzheimer, antiglycation, antibacterial, and hepatoprotective effects. From the results, it is evident that S. foetida contains various bioactive compounds and is recommended as a plant of pharmaceutical importance.