Preparation, Characterisation and Antifungal activity of Silver Nanoparticles prepared with Fresh Extract of Aconitum heterophyllum leaves

Author:

Akhtar Rasool Mohammad1,Kumar Gautam Girendra2,Prasad Panda Durga1,Bhattacharya Arin1,Jain Ritesh3

Affiliation:

1. Professor, J. K. College of Pharmacy, Bilaspur (CG).

2. Director and Professor, Sri Ram College of Pharmacy, Muzaffar Nagar (UP)

3. Department of Pharmacology, School of Pharmacy, CEC, Bilaspur, C.G.

Abstract

A Silver nanoparticles of the green approach for the synthesis of well – stabilized silver nanoparticles is described the nanoparticles will be biosynthesized by adding Silver nitrate with extract in deionized water, silver nitrate and extract of Aconitum heterophyllum with different concentrations. The phytochemical extract from this plant is more suitablefor large-scale biosynthesis of silver nanoparticles. Nanoparticles (NPs) prepared with plant extract are more stable, suitable and fastertherapeutic efficacyagainstfungal infection. Moreover, the preparations of silver nanoparticles with plant extract are more uniform in shape and size. The advantages of using plant and plant-derived materials for biosynthesis of silver nanoparticles have attract the interest ofresearchers due to its better mechanisms in successful formation ofsilver nanoparticles.Themetallic structurer were characterized using various methods. The AgNPs exhibit a maximum absorption at 430nm in Ultraviolet Spectroscopy, while the X-Ray diffraction indicates that they were crystalline in nature, including high resolution transmission electron microscopy, energy dispersive X-Ray Diffraction. It was confirmed by the electronic microscopic analysis that the spheres prepared with silvermetal and plant extract are uniform nanoparticle shape and size.

Publisher

A and V Publications

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