The association between Triglyceride-Glucose index and Hypertension statues (stages and phenotypes) in Type II Diabetes Mellitus

Abstract

Background: Hypertension is strongly associated with insulin resistance (IR) in Type II Diabetes Mellitus (T2DM). Triglyceride-glucose index (TyG-G index) is an effective and new marker to verify IR. Aim: To evaluate the association of TyG-G index with blood pressure categories and progression of hypertension stages and phenotypes in T2DM. Methods and Materials: The study was conducted on 98 T2DM patients between November 2020 and December 2021. Patients were classified into five categories according to hypertension stages and phenotypes to evaluate the TyG-G index. Lipid, obesity, and glycemic indicators were evaluated. Results: Elevated TyG-G index found in patients with hypertension; SBP and DBP phenotypes, P =0.001. 50% of patients were hypertensive-stage 2 and significantly associated with elevated TyG-G index. Conclusion: TyG-G index of cutoff (8.8) is a non-IR marker with high sensitivity (71%) and specificity (63%) for blood pressure progression (stages, phenotypes) independently of age, sex, lipid, obesity, and glycemic indicators.