Phytochemical Analysis and Identification of Bio-active compounds in Ethanolic leaf extract of Amaranthus spinosus

Author:

Boro Sangita1,Bharadwaj Bhriganka1,Unni Balagopalan2,Kumar Rai Avdhesh3,Bhattacharjee Minakshi4

Affiliation:

1. Programme of Microbiology, Faculty of Science, Assam Down Town University, Assam.

2. Adviser Research, Assam Down Town University, Assam and Director- Academic Research, GEMS Arts and Science College, Kerela.

3. Assistant Research Officer, DBT Centre for Molecular Biology and Cancer Research, Dr. B. Barooah Cancer Institute, Assam.

4. Programme of Biotechnology, Faculty of Science, Assam Down Town University, Assam.

Abstract

The leaves of Amaranthus spinosusis considered to have properties to treat menstrual disorder, gastroenteritis, gall bladder inflammation, abscesses, arthritis and also snakebiteThe phytochemical analysis confirmed the presence of alkaloid, carbohydrate, glycoside, saponin, phenolic compounds, phytosterol, proteins, amino acids, flavonoids and tannins by conventional biochemical methods. The Gas Chromatography-Mass Spectrometry analysis of the ethanolic leaf extracts of Amaranthus spinosus established the existence of compoundssuch as 4- Piperidinone, 2,2,6,6-Tetramethyl (RT 19.573), Methyprylon (RT 19.583), 2 Hexanol, 2- Methyl (RT 10.629). FT-IR analysis revealed the presence of various functional compounds such as alcohol, phenol alkanes, aromatic rings and aliphatic compounds. This study assures that the ethanolic leaf extracts of Amaranthus spinosus has many biologically active compounds apart from already reported phytochemicals which could be exploited for the development of plant-based drug.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference28 articles.

1. Choudhury A. Evaluation of physiochemical and phytochemical parametersof Amaranthus spinosus, International Research Journal of Pharmacy. 2012; 3(10):210-211; https://irjponline.com/admin/php/uploads/1456_pdf.pdf

2. Kawade, R. M., Ghiware, N. B., Sarje, S. K., andVadvalkar, S. M. A pharmacognostic and pharmacological review: Amaranthus spinosus. World Journal of Pharmaceutical Research. 2013; 2(6):99-110; https://doi.org/10.29252/nirp.bcn.8.6.503

3. Jhade, D., Ahirwar, D., Jain, R., Sharma, N. K., and Gupta,S. A pharmacological review: Amaranthus spinosus. Research Journal of Pharmacognosy and Phytochemistry. 2009; 1(3):169-172; https://rjpponline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacognosy%20and%20Phytochemistry;PID=2009-1-3-6

4. Boro, S., Bharadwaj, B., and Unni, B.G. Prickly Amaranth (Amaranthus spinosus Linn.): a Review on Phytochemistry and Pharmacological Activities. American Journal of Pharmatech Research, 2016; 6(5):81-92.http://ajptr.com/archive/volume-6/october-2016-issue-5

5. Majumdar, J., Boro, S., Bharadwaj, B., and Unni, B.G. Phytochemical analysis and Isolation of Compounds from Methanolic Leaf Extract of Amaranthus spinosus and its antimicrobial effect against Staphylococcus aureus. World Journal of Pharmaceutical and Life Sciences. 2017; 3(7): 100-103.https://www.wjpls.org/home/article_abstract/638

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