Review on Sensitivity and Selectivity of Colorimetric Sensor Based on Responsive Polymer against Pathogenic Bacteria

Abstract

Pathogenic bacteria cause severe cases in human health, especially pathology in infectious diseases. The incidence of bacterial resistance to antibiotics also seriously impacts human health, so a detection method that is more sensitive, fast, and easy is needed. Responsive polymers are biocompatible, non-thrombogenic, firm, elastic, flexible, and easy to shape, and have become the choice for colorimetric sensors against bacteria. This narrative review aims to determine the sensitivity and selectivity of responsive polymers as a sensor system against pathogenic bacteria. The compilation of this narrative review was traced through the PubMed database using the keyword "(sensitive polymers OR responsive polymers) AND (colorimetric detection OR colorimetry) AND (bacteria OR pathogen)". The inclusion criteria used were primary literature with the publication year 2010-2020. From these results, nine published articles that met the criteria for review were determined. Based on the analysis results, the responsive polymer has a sensitivity with a LOD range of 1-108 CFU/mL and high selectivity in colorimetric sensors to detect pathogenic bacteria.