Proficient protocol for synthesis of Quinoline and Pyrazole derivatives using greener reagent: Glycerol

Abstract

A forthright, effectual and more viable catalyst-free method has been developed for the synthesis of quinolone and pyrazole ring system in glycerol to achieve yields that were equivalent to or better than, those in conventional media. It is notable that the reaction was exclusively carried out in glycerol–acetic acid system, representing methodology is highly valuable from both environmental and economic points of view