Evaluation of Anti-asthmatic activity of Achyranthes aspera Linn root Extract

Author:

Ganesh S Shinde1,Kunkulol Rahul2,Narwane Sandeep2,Jadhav Ravindra1,Vikhe Dattaprasad3

Affiliation:

1. Department of Pharmaceutics, Institute of Pharmacy, loni.

2. Department of Pharmacology, Pravara Institute of Medical Science, Loni.

3. Department of Pharmacognosy, Pravara Rural College of Pharmacy, Pravaranagar.

Abstract

Asthma in chronic condition is very tedious to cure and which is very common disease. The aim of study was to evaluate anti-asthmatic activity root part of. A. aspera. Collection of root part of is done from Rahata District Ahmednagar (Maharashtra). For authentication of of Achyranthes aspera A. aspera Herbarium of plant was made and sent to Biological Survey of India, Pune. The collected material was proceeded for air dry at 35-40º C and then it was pulverized in electric grinder. Extraction of obtained powder was completed in ethanol,Water-ethanol and Petroleum ether by using Soxhlet Apparatus.. The presence of Steroids, flavonides, phenolic compound, glycosides, tannins, saponins, alkaloids and carbohydrates were revealed by phytochemical screening. The extract obtained were of aerial part of screened for anti-asthmatic activity. The Petroleum ether extract of root part was result the right side shift of dose Achyranthes aspera response curve in isolated goat chain and isolated guinea pig so it is indicating antiasthmatic action of drug extract.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference11 articles.

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