In-vivo studies to determine Hair Growth Potential of Poly Herbal Medicated Hair Oil in Female Swiss Albino Mice

Author:

JK Pandya1,MK Senghani1,PS Sukhramani1,BG Chaudhari2

Affiliation:

1. Veerayatan Institute of Pharmacy, At Post: Jakhania, Bhuj- Mandvi Highway, Mandvi- Kutch, Gujarat-370460, India.

2. Tolani Institute of Pharmacy, Adipur- Kutch, Gujarat- 370205, India.

Abstract

Hair loss is one of biggest problem of today’s human life throughout World. Alopecia, Baldness and hair loss are commonly found in the men as well as in female. Commonly available medicated hair oils in market for the treatment of hair disease are made up with mineral oil, which is proved to be carcinogenic in nature if applied for longer period of time. Hair plays a vital role in the personality of human and for their cure we use lots of cosmetic products. The fading (pigmentation problem), dandruff, alopecia (loss of hair) is the major problem associated with hairs. An Ayurveda is Indian traditional system of Medicine having major treatment across globe. The aim of study is to develop a poly herbal hair oil (PHO) formulation using Azadirachta indica, Rosa sinensis, Muraya koenigii, Lagenaria siceraria, Bacopa monieri, Lawsonia inermis, Eclipta alba, Embelica officinalis, coconut oil and Til oil, for better growth of hair and diminution in loss of hair (alopecia). The oil was prepared according to Ayurvedic Formulary of India and was standardized according to Protocol for Testing Ayurvedic, Siddha and Unani Medicines, Government of India. The physico-chemical evaluation was carried out for medicated hair oil. The pharmacological evaluations were performed through Pre-clinical Animal studies for qualitative, quantitative and mean- hair length studies.The statistical results of the study have demonstrated that 5% PHO possessed potent action on hair growth in the Female Swiss albino Mice animal’s model investigates as well as these provide a rationale in favor of its uses inside traditionally drug in favor of utilization in Baldness and other hair growth disorders.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference19 articles.

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2. KS, WA, AKV et al. Physiology and Anatomy of Hair in drug abusing cases. International Journal of Medical Toxicology and Forensic Medicine,2012;2(4):153-159, doi.org/10.22037/ijmtfm.v2i4(Autumn).3765.

3. Saraf S et al. Herbal Hair Cosmetics: Advancements and recent findings. World Journal of Pharmaceutical Research, 2014; 3(2): 3278-3294, ISSN 2277 – 7105.

4. Gupta S, KR. Hair Loss- An analysis and Updated Treatment. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 2015; 14: 77-81, doi:10.9790/0853-14727781.

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