Synthesis, Characterization and Biological Evaluation of some new Isoxazole and Pyrazole compounds for Anti-obesity drug

Abstract

The discipline of medicinal chemistry is dedicated to the discovery and development of new agents for treating diseases. Most of this activity directed to new natural or synthetic organic compounds. Development of organic compounds has grown beyond traditional synthetic methods. It now includes the new exciting new field of biotechnology using cells biochemistry to synthesize new compounds. Chemical synthesis is purposeful execution of chemical reactions to get a product or several products. Chemical synthesis is purposeful execution of chemical reactions to get a product or several products. The requirement is to synthesize novel molecules having good potential with high therapeutic index. Keeping in view the diverse therapeutic activities of Chalcones for the preparation of bioactive heterocycles, it was contemplated to synthesize a novel series of Chalcones. Attention has been focused on the substitution of acetophenone and benzaldehydes to achieve new anti-obesity profiles.