A Comprehensive Update on Nanoparticle in Targeting of Skin Cancer Therapy: Recent Updates, Challenges, and Future Perspectives

Abstract

Skin cancer is a leading cause of cancer-related mortality and disability worldwide. Nanoparticles may one day provide a highly targeted and effective means of combating skin cancer. This review article discusses nanoparticles' existing use, limitations, and prospects in skin cancer treatment. The data came from studies, reviews, and academic articles published within the previous five years. Thanks to nanoparticles, improved medication delivery, more individualized therapies, and more precise imaging techniques are all possible. Chemotherapy, targeted therapies, and combination medications all use nanoparticles like liposomes and dendrimers made of metals. Despite the positive results, there are still obstacles to overcome, such as bioavailability, toxicity, and regulatory hurdles. The review draws attention to these problems and stresses the necessity for further study and multidisciplinary cooperation. One way to treat skin cancer more thoroughly is to use multifunctional nanoparticles or to combine nanoparticles with emerging technologies such as immunotherapy and CRISPR. Researchers, physicians, and policymakers interested in using nanoparticles to treat skin cancer may find this helpful work.