Affiliation:
1. Department of Chemistry, College of Science, University of Diyala, Diyala, Iraq.
Abstract
This study was aimed to investigate the structure of bioactive components of Coriander Seed Oil (CSO) and their antimicrobial effects. Initially, the structural examination was conducted using various spectroscopic techniques, such as FTIR, and UV-visible spectroscopy, which are important in determining substituents, functional groups, and the presence of conjugated double bonds in CSO. From the FTIR spectra, a variety of sharp, strong, and weak peaks were specified relating to the main components of Linalol, and Decenolin CSO. The results of UV-visible spectroscopy confirmed the presence of Linalool as a major compound, and conjugated double bonds were also found. Furthermore, anti- microbial activity of CSO was studied against various types of bacteria. Strong bacterial inhibitory effects were observed, especially against S. aureus, with an average inhibition zone of 18 mm. It was also found from the structural characterization of CSO that the existence of Linalol is responsible for potential antibacterial activity. The main observation of this work is that CSO has antimicrobial activity even against methicillin-resistant Staphylococcus aureus.
Reference33 articles.
1. Mc Donald, S., Prenzler, P.D., Antolovich, M., Robards, K. Phenolic content and antioxidant activity of olive extracts. Food Chem. 2001:73; 73-8.
2. S. A. Mohite, R. R. Shah, N. R. Patel. Antimicrobial Activity of Leaves extracts of Jatropha curcas. Asian Journal of Pharmaceutical Research. 2018: 8; 1.
3. Nalla Priyanka, P. Brahmeswari, G. Raveendra Babu, M. Sowjanya, M. Ramayyappa. Evaluation of Anti-bacterial and Anti-inflammatory Activities of Ethanolic Extract of Hibiscus hirtus Linn. Leaves. Asian Journal of Pharmaceutical Research. 2022; 12:1.
4. Swini K, Mangesh K, Kailash V, Pratibha Cand Mahavir G. Phrmacognostic investigation on leaves of Citrus maxima (Burm.) Merr. (Rutaceae). International Journal of Pharmaceutical Sciences and Research. 2012; 3(12): 4913-4918.
5. Aliyu AB, Musa AM, Abdullahi MS and Oyewale AO. Phytochemical and antibacterialproperties of Ludwigia suffruticosa (Willd.) Oliv. ex O. Ktze (Onagraceae). International Journal of Pharmaceutical and Applied Sciences. 2008; 2(4): 1-5.