Physiological and Therapeutic Role of Calcitonin

Abstract

Homosapeins have been identified with over 50 hormones. Hormones control or regulate different biological processes. Among all, Calcitonin is one of theabandoned hormones. Calcitonin is released from the C-cell of the thyroid gland. Thyrocalcitonin is a type of neuroendocrine composed of 32 amino acids released from parafollicular cells(C-Cells) present in the thyroid gland in human beings and many other animals in the body. The utility of hormones is still under consideration. Calcitonin is physiologically involved in the maintenance of the calcium and phosphate levels in the blood. As diagnostic parameter utility is observed in the diagnosis of medullary thyroid cancer, C cell hyperplasia. Therapeutically the monoclonal antibodies derived from calcitonin are effective for the treatment of migraine. It possesses anodynic, cardioprotective, and peripheral nerve regeneration. Recent research shows the use of human analogue calcitonin as FDA approved second-line treatment for Paget’s disease. Calcitonin analogue shows its usefulness, especially in the case of bisphosphate tolerance. Calcitonin will be a research topic for future perspective. This study was conducted to the elaborate role of calcitonin in human physiologyThis study involved the utilization of standard databases like PubMed and google scholar to determine the different roles of calcitonin in pathological and physiologicalThe present study shows that calcitonin levels are not only raised in diagnosing C -cell hyperplasia and medullary thyroid cancer, but other conditions are responsible for increased calcitonin in the systemic circulation.The current study manifests the role of calcitonin as a diagnostic parameter and pharmacological treatment. It was observed that calcitonin can be helpful in another pathological disease.