Fourier Transform Infra-Red Spectroscopy: Recent advances and prospective in Analytical Method Development and Validation

Abstract

In recent years, Fourier Transform Infrared (FTIR) spectroscopy has emerged as a powerful analytical technique not only in the Pharmaceutical field but also in agriculture, petroleum and environmental analysis. FTIR Spectroscopy can turn out to be a potent alternative over other analytical techniques for method development and validation as this process is fast and sensitive, robust and accurate and less time consuming as it does not requires any sample preparation and also does not requires any kind of solvents for dilutions. It is eco-friendly as it does not require any toxic organic solvents. This technique does not require organic solvents, which is one of the main advantages over the other analytical techniques. It also bypasses the sample preparation steps for any kind of sample i.e. for solid or liquid samples, which makes this technique faster and rapid when compared to other analytical techniques. Therefore the technique has emerged as a powerful analytical technique for both qualitative and quantitative estimation of drugs.