Preclinical Evaluation of a Homeo Formulation ‘Force Drop’ for its androgenic activity

Author:

Haldar Soumyajit1,Saha Anumita1,Majumdar Mrityunjoy1,Paul Sumit1,Paul Monit2,Roy Sourav1,Mukhopadhyay Bappa3,Roy Prodip1

Affiliation:

1. Department of Pharmacology, Netaji Subhas Chandra Bose Institute of Pharmacy, Roypara, Chakdaha, Nadia, 741222, West Bengal, India.

2. Department of Pharmaceutical Chemistry, Netaji Subhas Chandra Bose Institute of Pharmacy, Roypara, Chakdaha, Nadia, 741222, West Bengal, India.

3. N. P. Dutt and Son, 55, Pramanick Ghat road, Kolkata-700036.

Abstract

In this study we have evaluated the preclinical observation of the Force Drop on the mature male albino rats. The Force Drop is the product of N. P. Dutt and Son, Kolkata, in this product have many herbal plants with their androgenic activity. Mainly we have compared this product with the activity of testosterone. We have used testosterone in this study as a standard drug or chemical. In this study we have grouped the all animals in 4 and each group has 6 animals, there are one untreated, treated with testosterone or standard group, another two groups are low dosed Force Drop treated group and last one is higher dosed Force Drop treated group. The study has shown that the animals of standard group increased the dry weight of androgen sensitivity tissues and overall body weight and the animals of treated groups or Force Drop Ptreated groups increased the dry weight of sensitivity tissues and overall body weight but lesser the testosterone treated group and more than untreated group. But the lower dosed Force Drop Ptreated group increased weight of androgen sensitivity tissues and body weight which are less than higher dosed Force Drop treated animal group and more than untreated group. And the higher dosed Force Drop treated animals group increased weight much more than the untreated group of animals and lower than standard group or testosterone treated group.

Publisher

A and V Publications

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