New Spectrophotometric Method for the Estimation of Fenofibrate-Reference-Cited by-同舟云学术

New Spectrophotometric Method for the Estimation of Fenofibrate

Published:2024-06-25 Issue: Volume: Page:2753-2756
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Mathrusri Annapurna Mukthinuthalapati¹,Tejasri Pothina¹,Narendra Angirekula¹

Affiliation:

1. GITAM School of Pharmacy, GITAM (Deemed to be) University, Visakhapatnam, India-530045.

Abstract

Fenofibrate is a Antihyperlipidemic used to treat cholesterol. New spectrophotometric technique have been developed for the estimation of Fenofibrate in pharmaceutical dosage form. Double beam UV-VIS spectrophotometer (SHIMADZU Model UV-1800) was used for the present study. Fenofibrate has shown linearity over the concentration range 0.5-40 µg/mL for acetate buffer (pH 4.0), phosphate buffer (pH 7.8), 0.1M sodium hydroxide and 1-40 µg/mL for phosphate buffer (pH 5.8), and distilled water respectively and the methods were validated as per ICH guidelines. The proposed methods are simple, economical and can be successfully applied for the assay of Fenofibrate in pharmaceutical dosage forms.

Publisher

A and V Publications

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