In-vitro Cytotoxic and Antioxidant Activity of Bauhinia racemosa Root-Reference-Cited by-同舟云学术

In-vitro Cytotoxic and Antioxidant Activity of Bauhinia racemosa Root

Published:2021-06-29 Issue: Volume: Page:3333-3336
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

P. Aravanan¹,S Jayakumari²

Affiliation:

1. School of Pharmaceutical Sciences, Vel’s Institute of Science, Technology and Advanced Studies (VISTAS), Pallavaram, Chennai.

2. Department of Pharmacognosy, School of Pharmaceutical Sciences, Vels University, Chennai - 600117.

Abstract

Objective: To evaluate cytotoxic and antioxidant activity of the plant Bauhinia racemosa root by in-vitro cell line analysis. Methods: MCF-7 cell lines were used for the study to find the inhibitory concentration of the extract. DPPH and NO scavenging assays were performed to study the antioxidant nature of the extract. Results and Conclusion: In MCF-7 cell line cytotoxicity effect was observed in tested sample concentrations in 48 hours treatment, it also revealed that increased concentration of drug shown increased cytotoxicity over the MCF-7 cell lines. DPPH and NO scavenging Assay revealed a concentration dependent radical scavenging capacity of the tested sample concentrations of Bauhinia racemosa root spectrophotometrically.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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