An Updated Comprehensive Review on Nanosponges – Novel Emerging Drug Delivery System

Abstract

Medical researchers found problem in targeting the drug delivery. The Nanotechnology has become highly competitive and rapidly evolving as more and more developments in delivery systems are being integrated to optimize the efficacy and cost effectiveness of therapy. The development of new and complex molecules Nano sponges has potential to solve this problem. Nano sponge drug delivery system has emerged as one of the most promising fields in pharmaceutics. Nano sponges consist of nonporous particles that can suspend or entrap a wide variety of substances, and then be incorporated into a dosage form. Nano sponge play vital role in targeting drug delivery in a controlled manner. Both lipophilic and hydrophilic drugs are incorporated in Nano sponge. The outer surface is typically porous, allowing controlled release of drug. Nano sponge delivery system (NDS) provides increased efficacy with enhanced safety, extended product stability, improved formulation flexibility, reduced side effects and superior aesthetic properties in an efficient and novel manner. Adding up they are non-irritating, non-mutagenic, non-allergenic and non-toxic. Topical drug delivery system also faced many problems like poor permeability, skin irritation, allergic reactions etc. The new developed colloidal system called Nano sponge has potential to overcome this problem. In short Nano sponges encompass many favorable characteristics which make them a versatile drug delivery vehicle. The present review explores on the preparation methods, applications of Nano sponges in the field of drug delivery.