Acid Catalyzed Synthesis of substituted-n-((1, 3-diphenyl-1h-pyrazol-4-yl) methyl) benzenamine-Reference-Cited by-同舟云学术

Acid Catalyzed Synthesis of substituted-n-((1, 3-diphenyl-1h-pyrazol-4-yl) methyl) benzenamine

Published:2021-12-28 Issue: Volume: Page:6442-6446
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Hanumantappa Havale Shrikant¹,Singh Bhavani¹,Dwivedi Jaya¹,kishore Dharma¹,Rao S. Venkat²

Affiliation:

1. Department of Chemistry, Banasthali University, Banasthali, Rajasthan, India – 304022.

2. Department of Chemistry, SMS Research Center (ADSIR Approved Facility), SMS Pharmaceuticals Ltd; Hyderabad, Telangana, India 500043.

Abstract

A new derivative synthesis of Substituted-N-((1, 3-diphenyl-1h-pyrazol-4-yl) methyl) benzenamine has attempted by using commonly available key starting materials Acetophenone (1) and substituted phenyl hydrazine in presence of sulfuric acid catalyst and alcohol solvent to afford potential antiviral active analogues. The synthesis proceeds through Vilsmeier-Haack reaction followed by reductive amination by using sodium borohydride.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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