In-vitro Comparative study on blood clotting time of some Plants Extracts and Heparin when Infected with Snakebite

Abstract

Around the world, snake bite injuries are still life threatening and require intensive care. The diagnose and treatment to toxic snake bites is the insufficient information, within the management of anti-toxin therapy, is not provided in clinical practice. In this comparative study, water extracts of Allium sativum, Allium cepa and Nigella sativa in different concentrations and heparin powder was used on human blood which is free from diseases. The common desert snake poison was used to compare the anti-coagulation time of the above plant extracts. Among three extracts Nigella sativa extract showed more time of coagulation of blood when treated with the snake poison. The results of the present study confirms the traditional medicinal use of selected plants and evidence for the best substances impact in the delay of blood clotting against snake bites of those plants. Further research is going on to isolate bioactive compounds.