Niosomes: The Current and Future perspectives in Drug Delivery System

Author:

Singh Bhupendra1,Sharma Pooja1,Bose Sujit2,Thakur Jyoti1,Saini Geetanjali1,Vyas Manish2

Affiliation:

1. Abhilashi College of Pharmacy, Nerchowk, Mandi H.P, India.

2. Lovely Faculty of Applied Medical Sciences, Lovely Professional University, Phagwara, P.B.

Abstract

There are many problems with the conventional dosage form of various drugs and one of them is dosing frequency in which patients have to take the drug again and again throughout the day which is very difficult mainly for the elder patient. So, to overcome this problem the approach of a novel drug delivery system (NDDS) is used to replace the conventional drug delivery system. NDDS mainly deals with sustained release of drugs which is effective to reduce the dosing frequency. Niosome is one of the best approaches of a novel drug delivery system, in which the drug in solution form is enclosed in vesicle which is made up of non-ionic surfactants. In the case of liposome which is another part of NDDS vesicles is made up of phospholipids. Niosome formulation is a powerful tool to resolve the issue of insolubility and the low bioavailability of drugs. This paper overviews the various methods of preparation of Niosome along with its pharmaceutical applications.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference50 articles.

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3. Fang J.Y. et al., Characterisation and stability of various liposomes –encapsulated enoxacin formulations. Chem. Pharm Bull.2001; 45: 1504-1509.

4. Kamath M.P. et al., Indian Journal of. Experimental Biology, 2000; 32(2): 113- 118.

5. Naresh RAR. et al., Kinetics and Tissue Distribution of Niosomal Bleomycin in Tumor Bearing Mice. Indian Journal of Pharmaceutical Sciences.1996; 230.

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