Evaluation of Antibiotics Utilization on Pediatric Inpatients in H. Adam Malik Hospital Medan, Indonesia

Abstract

Infectious disease remains one of the important public health issues, particulary in developing countries. Although the use of antibiotic applies to all ages, antibiotic for pediatric needs special attention. The fact, antibiotic prescribed for pediatric in Indonesia still commonly found (~90%). The indiscriminate use of antibiotics in pediatric will increase the risk of infection, such as eliminating the good bacteria in the body, damaging the imperfect organs, and cause mutation that will lead to antibiotic resistance, so antibiotics become less effective in treating. The aim of this study was to determine antibiotics prescribing profile for pediatric inpatient in H. Adam Malik hospital Medan, Indonesia in 2019. This study was using a retrospective cross-sectional method study which conducted from July-August 2020 with data from June to December 2019. From H. Adam Malik hospital Medan, there were 325 medical records contained antibiotic that made as sample. The antibiotic that mostly prescribed for pediatric inpatients was cephalosporin for 325 medical records (47%) which was ceftriaxone. There were 270 (60%) of the 453 total of antibiotics used which mismatch duration. There were 39 (8.61%) of the 453 total of antibiotics used with mismatch dose and the most dosage form was injection 211 (47%). It shows that ceftriaxone was the most prescribed antibiotic for pediatric inpatients in H. Adam Malik hospital Medan and there is still mismatch in dose and duration of use in antibiotic prescribing for pediatric. Prescribers should improve prescribing practices and make it more rational.