Synthesis and pesticidal activity of some 4-Azolylmethyl-1,3-dioxolanes, based on cyclic ketones-Reference-Cited by-同舟云学术

Synthesis and pesticidal activity of some 4-Azolylmethyl-1,3-dioxolanes, based on cyclic ketones

Published:2021-12-28 Issue: Volume: Page:6417-6422
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Talismanov V.S.¹,Popkov S.V.²,Zykova S.S.³,Karmanova О.G.¹

Affiliation:

1. Department of Chemistry, Moscow Institute of Physics and Technology, Dolgoprudny, Moscow Region, Russian Federation.

2. Department of Chemistry and Technology of Organic Synthesis, D. Mendeleev University of Chemical Technology of Russia, Moscow, Russian Federation.

3. Department of Pharmacology, Perm State Pharmaceutical Academy, Perm, Russian Federation.

Abstract

In vitro tests of substituted 1,3-dioxolanes, based on cyclic ketones and substituted with 1H-1,2,4-triazole and 1H-imidazole showed a fungicidal activity lower than the activity of the triadimefon, and spiroxamine. Studied compounds in the entire concentration range: from 0.001 to 10 mg/L showed noticeable retardant properties. The target compounds were derived by cyclization of substituted cyclohexanones with epichlorohydrin followed by alkylation of the derived 2 chloromethyl-1,3 dioxolanes of sodium salts of imidazole or 1,2,4-triazole.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference34 articles.

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2. Talismanov VS, Popkov SV, Karmanova OG, Zykova SS. Synthesis and fungicidal activity of substituted 1-[(1,3-dioxolan-4-yl)methyl-1H-imidazoles and 1-[(1,3-dioxolan-4-yl)methyl]-1H-1,2,4-triazoles based on arylidene ketones. International Journal of Pharmaceutical Research. 2019; 11(2): 315-319. doi.org/10.31838/ijpr/2019.11.02.051

3. Talismanov VS, Popkov SV, Zykova SS, Karmanova OG. Synthesis and study of the fungicidal activity of substituted 1-[(2-benzyl-1,3-dioxolan-4-yl)methyl]-1H-imidazoles, 1-[(2-benzyl-1,3-dioxolan-4-yl)methyl]-1H-1,2,4-triazoles and 4-[(2-benzyl-1,3-dioxolan-4-yl)methyl]-4H-1,2,4-triazoles. Journal of Pharmaceutical Sciences and Research. 2018; 10: 1780-1783

4. Talismanov VS, Popkov SV, Zykova SS, Karmanova OG, Tsaplin GV. Study of the stereoisomeric composition of biologically active substituted 1-[(1,3-dioxolan-4-yl)methyl]-1H-1,2,4-triazoles and 1-[(1,3-dioxolan-4-yl)methyl]-1H-imidazoles by NMR spectroscopy techniques. Journal of Pharmaceutical Sciences and Research. 2018: 10: 2041-2044

5. Talismanov VS, Popkov SV, Karmanova OG, Zykova SS. Synthesis of 2-(4-aminophenyl)-4-triazolylmethyl-1,3-dioxolanes - intermediates of biologically active compounds. Journal of Pharmaceutical Sciences and Research. 2017; 9: 1985‒1988.