The effect of vitamin D and Physical exercise on glycaemic control in patients with Type 2 Diabetes Mellitus(DM)

Abstract

Background: The purpose of this study was to find correlation between vitamin D, Physical exercise on glycaemic control in patients of type2DM. Methods: The study was conducted from November 2019 to December 2020 among subjects above 40 years of age at sub-district hospital Sopore, North Kashmir. Total 400 patients diagnosed with diabetes were registered for the study. Questionnaire containing relevant patient information was collected at regular intervals. Statistical analysis were performed. Results: Biochemistry values in the studied subjects with Type2DM compared to healthy controls in the study revealed that fasting glucose level,HbA1c,LDL,triglycerides,uric acid were higher inT2DM group compared to the control group. The results of our study showed that Vitamin D deficiency, lack of physical exercise, family history of T2DM, hypertension and smoking were significant predictors of diabetes. In Type2DM patients, mean vitamin D value was 21.45ng/ml opposed to 40ng/ml in the control group. Also physical activity was found to be higher in control group when compared to cases with p -value less than 0.00001. Also family history of DM was significantly higher in cases when compared to control group with p-value of 0.044.There was also statistically significant difference when parameters like HTN and smoking were compared (both higher in cases as against the control group) between two groups with p value 0.044 and 0.029 respectively. Conclusion: Vit D, physical exercise,family history of diabetes may be contributing factors for the rising burden of diabetes globally and in India.We need to take cognisance of the factors leading to the rising global burden of DM and take appropriate and necessary measures to stop this growing menace.