Screening of Novel Hybrid Combinations of Synthetic Drugs with Plant Extracts for its In vitro Antioxidant Activity

Author:

Savant Chetan1,Kulkarni Venkatrao1,Habbu Prasanna2,Kulkarni Preeti1,Majeed Muhammed3,Nayak Mahadeva3

Affiliation:

1. Department of Pharmacology, SET’s College of Pharmacy, Dharwad-580002, Karnataka, India.

2. Department of Pharmacognosy, SET’s College of Pharmacy, Dharwad- 580002, Karnataka, India.

3. SAMI Labs Limited, R&D Peenya Industrial Area, Bangalore- 560058, Karnataka, India.

Abstract

The present experiment was carried out with the aim to screen selected herb-drug for its antioxidant activity in combination and individually. The antioxidant activity of test samples were estimated by 2,2 Diphenyl -1-picryl hydrazyl (DPPH) radical scavenging activity, hydroxyl radical scavenging activity, reducing power assay. All the selected herb-drug combinations have shown significant antioxidant activity in all three antioxidant procedures compared to individual herb or drug sample. Hence, it may be concluded that herb-drug combinations have better antioxidant potential than alone.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference27 articles.

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3. Park PJ et al. Purification and characterization of antioxidative peptides from protein hydrolysate of lecithin free egg yolk. Journal of the American Oil Chemists' Society. 2001;78: 651‐656.

4. Jain A et al. Phytochemical composition and antioxidant activity of methanolic extract of Ficus benjamina (moraceae) leaves. Research Journal of Pharmacy and Technology. 2013; 6(11): 1184-1189.

5. Wiysonge CS et al. Beta-blockers for hypertension. Cochrane database of systematic reviews. 2017(1).

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