A Review on Progressive Trends in Pharmaceutical Nano Emulsions and their Assessment

Abstract

This review aimed to deliver the progressive trends and need for research activities in the area of liquid bi-phasic systems i.e., Nano emulsion (NE). These categories of drug delivery system (DDS) are progressive modes for providing and increasing the bioavailability of non-aqueous drugs and the drug which have increased the first-pass metabolism. The NE's can be framed by either high or low energy techniques. High-pressure homogenization, micro fluidization, and ultra-sonication are involved in High energy techniques whereas the phase inversion emulsion forming method and the self-NE method are involved in low energy techniques. High energy techniques are having lower usage when compared to low energy techniques due to their high consumption of energy, hence low energy techniques are more operative and do not need any sophisticated devices. Even though high energy techniques are more suitable for food-grade emulsion as they need a reduced amount of surfactant than low energy techniques. Methods for formulation of NE DDS are overlying in nature, exclusively in the process of low energy techniques. This review gives the eminence of NE'S by comparing previous research carried over it.