Potential Test of Soy-yamghurt against Antidiabetic in male white rats (Rattus norvegicus) Streptozotocin induced

Author:

Handayani Tien Wahyu1,Anggi Viani1,Afrizal Afrizal1,Magfirah Magfirah1,tandi Joni1

Affiliation:

1. College of Pharmaceutical Sciences, Pelita Mas Palu, Central Sulawesi, 94111 Indonesia.

Abstract

Background: Soy-yamghurt is a fermented product of soy and sweet potato juice made from the addition of lactic acid bacteria and is thought to have antioxidant abilities, function to repair pancreatic cells, and reduce blood glucose levels. Aim: This study aims to determine the potential of soy-yamghurt probiotic drinks to decrease blood glucose levels of male white rats (Rattus novergicus). Method: This study used 30 rats divided into six treatment groups, namely normal control (NaCMC), negative control (streptozotocin+NA CMC), positive control (streptozotocin+glibenclamide), treatment formula 1 (streptozotocin+sweet potato juice+ soybean juice (1:1), formula 2(streptozotocin+sweet potato juice+soybean juice (1:2)), and formula 3(streptozotocin+sweet potato juice+soybean juice (2:1)). Results: The results showed that the average blood glucose levels were normal control (100.4mg/dL), negative control (298.8mg/dL), positive control (81.2mg/dL), formula 1(178.4mg/dL), formula 2(108.0mg). /dL), formula 3(134.4mg/dL). Conclusion: soy-yamghurt affects reducing blood glucose levels with an effective formula, namely formula 2 by giving 3.4ml.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

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