Recent Trends in Floating Drug Delivery System

Author:

Parida D R1,Kharia A A1,Choudhary N K1

Affiliation:

1. Department of Pharmacy, (B R Nahata College of Pharmacy), Mandsaur University, Rewas Dewda Road, SH - 31, Mandsaur, Madhya Pradesh- 458001.

Abstract

Conventional immediate release dosage forms does not control the drug release which leads to low oral bioavailability and more toxic effects. This happens due to multiple dosing and fluctuations in the plasma drug concentrations. Retention of the dosage forms in a specific region of the GIT provides more benefits, for those drugs which have poor absorption in stomach, low solubility and degradation in alkaline pH. FDDS is one among the important system with gastric retention properties. Formulations designed as FDDS, controls the rate of drug release by prolonging the gastric retention for extended hours and improves the absorption as well as bioavailability. This article provides information on recent trends of research and development in FDDS with a special emphasis on its importance for oral controlled drug delivery system. This review article also provides information on category of drugs and different polymers used for FDDS.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference61 articles.

1. Narang N: An updated review on floating drug delivery system (FDDS). International Journal of Applied Pharmaceutics. 3 (1); 2011: 1-2.

2. ShwetaArora et al, Floating Drug Delivery Systems- A Review, AAPS PharmSciTech 2005; 6 (3) Article 47

3. Moursy NM et al, Formulation and evaluation of sustained release floating capsules of Nicardipine hydrochloride. Pharmazie. 2003;58:38Y43.

4. Erni W and Held K: The hydrodynamically balanced system-a novel principle of controlled drug release. Eur Neurol. 1987;27:215Y275.

5. Menon A, Ritschel WA and Sakr A: Development and evaluation of a monolithic floating dosage form for furosemide. J Pharm Sci. 1994; 83:239Y245.

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