Recent Trends in Floating Drug Delivery System

Abstract

Conventional immediate release dosage forms does not control the drug release which leads to low oral bioavailability and more toxic effects. This happens due to multiple dosing and fluctuations in the plasma drug concentrations. Retention of the dosage forms in a specific region of the GIT provides more benefits, for those drugs which have poor absorption in stomach, low solubility and degradation in alkaline pH. FDDS is one among the important system with gastric retention properties. Formulations designed as FDDS, controls the rate of drug release by prolonging the gastric retention for extended hours and improves the absorption as well as bioavailability. This article provides information on recent trends of research and development in FDDS with a special emphasis on its importance for oral controlled drug delivery system. This review article also provides information on category of drugs and different polymers used for FDDS.